Endocrine Abstracts

Introduction: Abnormalities in the development and migration of the thyroid gland are known to produce ectopic thyroid tissue, usually in the midline between the tongue base and the diaphragm. Hashimoto’s thyroiditis involving ectopic thyroid tissue is particularly unusual. Herein we report a case of Hashimoto’s thyroiditis developing in a midline thyroid cervical mass.Observation: A 55-year-old man was referred for hypothyroidism. His physical...

Introduction: Cardiothyreosis (CT) is the most frequent and dangerous complication of hyperthyroidism (HT). It is defined as an association of HT with severe heart abnormalities such as: rhythmic troubles, heart and/or coronary insufficiency. The aim of our study was to describe the frequency and the clinical characteristics of CT in Graves’ disease (GD).Methods: Patients with GD were enrolled into a retrospective study. The prevalence and the clini...

Introduction: Graves’ ophthalmopathy (GO) is an autoimmune disorder affecting the retro-orbital tissues. It represents the main extra- thyroidal expression of Graves’ disease (GD). Its onset and progression are influenced by several factors that are potentially modifiable. The aim of this study was to identify risk factors for severe GO.Methods: Patients with GD were enrolled into a retrospective study. We compared possible risk factors and var...

Introduction: The syndrome of resistance to thyroid hormone is a rare inherited disorder characterized by elevated circulating thyroid hormones, failure to suppress pituitary thyroid stimulating hormone (TSH) and variable tissue target hyposensitivity to thyroid hormone action. We reported the case of a RTH syndrome with a novel mutation.Case report: A 15-year-old girl was investigated for visual hallucinations and behavior disorders. Her medical history...

Introduction: Metabolic syndrome is closely related to abdominal obesity. Classic anthropometric indices such as bmi and waist circumference have been used for the screening of metabolic syndrome.Recently, it has been reported that waist to height ratio is more closely associated with insulin resistance.The aim of the present study was to assess the relationship between waist to height ratio and components of metabolic syndrome amo...

Introduction: Hemochromatosis is a disorder caused by an excess of iron deposition in the parenchymal cells that leads to organ dysfunction. In patients with secondary hemochromatosis due to multiple blood transfusions, endocrinopathies such as diabetes mellitus, hypopituitarism frequently develop.Herein we report the case of a patient with B-thalassemia major who developed diabetes mellitus, hypopituitarism and primary hypoparathyroidism due to secondar...

Introduction: Mixed gonadal dysgenesis with 45X/46XY mosaicism is considered to be a rare disorder of sex development. This condition is characterized by a phenotypically very heterogeneous clinical presentation. In fact, the individuals with 45X/46XY mosaicism ranged from phenotypically normal men with azoospermia, going through individuals with genital ambiguity, to women with Turner syndrome.Herein, we describe a phenotypically Turner-like female with...

Introduction: Simultaneous occurrence of acute pancreatitis and diabetic ketoacidosis represents a very rare complication of antipsychotic medications.Herein we report the case of acute pancreatitis and diabetic ketoacidosis in a non-diabetic patient while on treatment with haloperidol, chlorpromazine and carbamazepineCase report: Mr. Z A is a 50-year-old non-diabetic man who was diagnosed with psychotic disorder and treated with h...

Introduction: Riedel thyroiditis is a rare form of infiltrative and fibrotic disease of the thyroid which may involve neighbouring tissues. The main differential diagnosis of Riedel thyroiditis includes malignant tumors and fibrosing Hashimoto’s thyroiditis.Herein, we report a case of concurrent Riedel’s disease and Hashimoto’s thyroiditis.Observation: A 45-year-old woman was diagnosed with goiter and hypothyroidism....

Introduction: Renal complications in Graves’ disease are rare and may be related either to the disease itself or secondary to antithyroid drugs.Methods: We report seven cases of renal damage in patients with Graves’ disease treated with Benzylthiouracyl collected over a period of 14 years.Results: There were seven women with a mean age of 37.86±14.25 years (19–61 years).Six patients develo...